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Synthesis and characterization of aCD47-CATE nanoplatform. (A) The preparation of aCD47-CATE nanoplatform. (B) UV-Vis absorption spectra of Croc under different pH. (C) The morphology of the aCD47-CATE nanostructure as visualized by transmission electron microscopy (TEM), scale bar = 100 nm (up) and scanning electron <t>microscope</t> <t>(SEM),</t> scale bar = 200 nm (down). (D) Changes in the zeta potential that occurred during the synthesis steps for both CATE and aCD47-CATE nanoplatform. Data are presented as mean ± SD (n = 3). (E) A characteristic high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) micrograph, presented alongside the associated elemental distribution maps for the aCD47-CATE nanoplatform. (F) NIR-II thermal images of the aCD47-CATE nanoplatform in a phantom under 1064 nm laser irradiation at different power densities (0.5, 1.0, 1.5, 2.0 W/cm 2 ) for 360 s. (G) Graphs depicting the temperature rise for the aCD47-CATE NPs under different laser power at 1064 nm laser irradiation. (H) Multiple heating cycles of aCD47-CATE nanoplatform under 1.0 W/cm 2 at 1064 nm laser irradiation.
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Synthesis and characterization of aCD47-CATE nanoplatform. (A) The preparation of aCD47-CATE nanoplatform. (B) UV-Vis absorption spectra of Croc under different pH. (C) The morphology of the aCD47-CATE nanostructure as visualized by transmission electron microscopy (TEM), scale bar = 100 nm (up) and scanning electron <t>microscope</t> <t>(SEM),</t> scale bar = 200 nm (down). (D) Changes in the zeta potential that occurred during the synthesis steps for both CATE and aCD47-CATE nanoplatform. Data are presented as mean ± SD (n = 3). (E) A characteristic high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) micrograph, presented alongside the associated elemental distribution maps for the aCD47-CATE nanoplatform. (F) NIR-II thermal images of the aCD47-CATE nanoplatform in a phantom under 1064 nm laser irradiation at different power densities (0.5, 1.0, 1.5, 2.0 W/cm 2 ) for 360 s. (G) Graphs depicting the temperature rise for the aCD47-CATE NPs under different laser power at 1064 nm laser irradiation. (H) Multiple heating cycles of aCD47-CATE nanoplatform under 1.0 W/cm 2 at 1064 nm laser irradiation.
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Synthesis and characterization of aCD47-CATE nanoplatform. (A) The preparation of aCD47-CATE nanoplatform. (B) UV-Vis absorption spectra of Croc under different pH. (C) The morphology of the aCD47-CATE nanostructure as visualized by transmission electron microscopy (TEM), scale bar = 100 nm (up) and scanning electron <t>microscope</t> <t>(SEM),</t> scale bar = 200 nm (down). (D) Changes in the zeta potential that occurred during the synthesis steps for both CATE and aCD47-CATE nanoplatform. Data are presented as mean ± SD (n = 3). (E) A characteristic high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) micrograph, presented alongside the associated elemental distribution maps for the aCD47-CATE nanoplatform. (F) NIR-II thermal images of the aCD47-CATE nanoplatform in a phantom under 1064 nm laser irradiation at different power densities (0.5, 1.0, 1.5, 2.0 W/cm 2 ) for 360 s. (G) Graphs depicting the temperature rise for the aCD47-CATE NPs under different laser power at 1064 nm laser irradiation. (H) Multiple heating cycles of aCD47-CATE nanoplatform under 1.0 W/cm 2 at 1064 nm laser irradiation.
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Synthesis and characterization of aCD47-CATE nanoplatform. (A) The preparation of aCD47-CATE nanoplatform. (B) UV-Vis absorption spectra of Croc under different pH. (C) The morphology of the aCD47-CATE nanostructure as visualized by transmission electron microscopy (TEM), scale bar = 100 nm (up) and scanning electron <t>microscope</t> <t>(SEM),</t> scale bar = 200 nm (down). (D) Changes in the zeta potential that occurred during the synthesis steps for both CATE and aCD47-CATE nanoplatform. Data are presented as mean ± SD (n = 3). (E) A characteristic high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) micrograph, presented alongside the associated elemental distribution maps for the aCD47-CATE nanoplatform. (F) NIR-II thermal images of the aCD47-CATE nanoplatform in a phantom under 1064 nm laser irradiation at different power densities (0.5, 1.0, 1.5, 2.0 W/cm 2 ) for 360 s. (G) Graphs depicting the temperature rise for the aCD47-CATE NPs under different laser power at 1064 nm laser irradiation. (H) Multiple heating cycles of aCD47-CATE nanoplatform under 1.0 W/cm 2 at 1064 nm laser irradiation.
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Synthesis and characterization of aCD47-CATE nanoplatform. (A) The preparation of aCD47-CATE nanoplatform. (B) UV-Vis absorption spectra of Croc under different pH. (C) The morphology of the aCD47-CATE nanostructure as visualized by transmission electron microscopy (TEM), scale bar = 100 nm (up) and scanning electron <t>microscope</t> <t>(SEM),</t> scale bar = 200 nm (down). (D) Changes in the zeta potential that occurred during the synthesis steps for both CATE and aCD47-CATE nanoplatform. Data are presented as mean ± SD (n = 3). (E) A characteristic high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) micrograph, presented alongside the associated elemental distribution maps for the aCD47-CATE nanoplatform. (F) NIR-II thermal images of the aCD47-CATE nanoplatform in a phantom under 1064 nm laser irradiation at different power densities (0.5, 1.0, 1.5, 2.0 W/cm 2 ) for 360 s. (G) Graphs depicting the temperature rise for the aCD47-CATE NPs under different laser power at 1064 nm laser irradiation. (H) Multiple heating cycles of aCD47-CATE nanoplatform under 1.0 W/cm 2 at 1064 nm laser irradiation.
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Synthesis and characterization of aCD47-CATE nanoplatform. (A) The preparation of aCD47-CATE nanoplatform. (B) UV-Vis absorption spectra of Croc under different pH. (C) The morphology of the aCD47-CATE nanostructure as visualized by transmission electron microscopy (TEM), scale bar = 100 nm (up) and scanning electron microscope (SEM), scale bar = 200 nm (down). (D) Changes in the zeta potential that occurred during the synthesis steps for both CATE and aCD47-CATE nanoplatform. Data are presented as mean ± SD (n = 3). (E) A characteristic high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) micrograph, presented alongside the associated elemental distribution maps for the aCD47-CATE nanoplatform. (F) NIR-II thermal images of the aCD47-CATE nanoplatform in a phantom under 1064 nm laser irradiation at different power densities (0.5, 1.0, 1.5, 2.0 W/cm 2 ) for 360 s. (G) Graphs depicting the temperature rise for the aCD47-CATE NPs under different laser power at 1064 nm laser irradiation. (H) Multiple heating cycles of aCD47-CATE nanoplatform under 1.0 W/cm 2 at 1064 nm laser irradiation.

Journal: Materials Today Bio

Article Title: Macrophage exosome-engineered nanoplatform with pH-responsive ratiometric photoacoustic and NIR-II fluorescence imaging for guided photothermal immunotherapy of hepatocellular carcinoma

doi: 10.1016/j.mtbio.2026.103058

Figure Lengend Snippet: Synthesis and characterization of aCD47-CATE nanoplatform. (A) The preparation of aCD47-CATE nanoplatform. (B) UV-Vis absorption spectra of Croc under different pH. (C) The morphology of the aCD47-CATE nanostructure as visualized by transmission electron microscopy (TEM), scale bar = 100 nm (up) and scanning electron microscope (SEM), scale bar = 200 nm (down). (D) Changes in the zeta potential that occurred during the synthesis steps for both CATE and aCD47-CATE nanoplatform. Data are presented as mean ± SD (n = 3). (E) A characteristic high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) micrograph, presented alongside the associated elemental distribution maps for the aCD47-CATE nanoplatform. (F) NIR-II thermal images of the aCD47-CATE nanoplatform in a phantom under 1064 nm laser irradiation at different power densities (0.5, 1.0, 1.5, 2.0 W/cm 2 ) for 360 s. (G) Graphs depicting the temperature rise for the aCD47-CATE NPs under different laser power at 1064 nm laser irradiation. (H) Multiple heating cycles of aCD47-CATE nanoplatform under 1.0 W/cm 2 at 1064 nm laser irradiation.

Article Snippet: Transmission electron microscope (TEM) images were captured with a JEOL JEM-2100, and Scanning Electron Microscope (SEM) images were obtained using a JEOL Model JSM-6490.

Techniques: Transmission Assay, Electron Microscopy, Microscopy, Zeta Potential Analyzer, Irradiation